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The CPJE exam has 90 questions and runs 2 hours.
These 10 free CPJE questions are organized by exam domain, so you can see how each part of the California Practice Standards and Jurisprudence Examination for Pharmacists blueprint is tested. Reveal the answer and explanation under each question.
A California community pharmacist receives a signed paper prescription for amoxicillin from a dentist. Every required element is present, the prescription is clinically appropriate, and the dentist says the certified electronic-prescribing system is temporarily unavailable. Under California's electronic-prescribing law, what is the pharmacist permitted to do?
Correct answer: C - Dispense it if otherwise valid; the pharmacist need not verify the exception
During final verification, a pharmacist sees a new prescription for methotrexate 10 mg daily, quantity 30, for rheumatoid arthritis. The patient's fill history shows methotrexate 10 mg once weekly plus folic acid. What should occur before the medication leaves the pharmacy?
Correct answer: B - Hold the prescription and clarify the intended frequency with the prescriber
An audit of a California outpatient prescription label finds the patient name, drug name and strength, directions, and condition listed in that order in 12-point sans serif type and occupying 55% of the label. The pharmacy's street address also appears inside that same cluster. Which revision brings the label into compliance?
Correct answer: A - Move the pharmacy address outside the patient-centered cluster
At 4:00 p.m. Monday, a pharmacy has only 18 of the 30 oxycodone immediate-release tablets ordered on a valid Schedule II prescription. The pharmacist partially fills it specifically because the pharmacy cannot supply the full quantity and records the amount dispensed. Under the federal stock-shortage rule, when may the remaining 12 tablets be supplied under the same prescription?
Correct answer: C - Within 72 hours after the first partial filling
Pulmonary clinic records show a 67-year-old with confirmed COPD who is not using a maintenance inhaler, a CAT score of 16, an mMRC grade of 2, one moderate exacerbation treated as an outpatient during the previous year, no exacerbation-related hospitalization, a blood eosinophil count of 90 cells/µL, and no history of asthma. Under the GOLD 2026 initial-treatment framework, which classification and regimen are most appropriate?
Correct answer: A - Group E; start a LABA plus a LAMA
A 29-year-old at 30 weeks' gestation received Tdap 2 years ago after a laceration. She has not received Tdap during the current pregnancy and has no contraindication to vaccination. What should the pharmacist recommend?
Correct answer: B - Administer Tdap now because it is recommended during every pregnancy at 27-36 weeks
Eight hours after linezolid is added to chronic sertraline therapy, a patient becomes agitated and diaphoretic, develops diarrhea and a temperature of 39.0°C, and has inducible ankle clonus with hyperreflexia. Which diagnosis and response best fit these findings?
Correct answer: D - Serotonin syndrome; stop the interacting agents and begin urgent supportive care
A pharmacy dispenses glipizide 10 mg instead of 5 mg. The patient takes one dose. After discovering the error, the pharmacist arranges glucose checks every two hours for the rest of the day; the patient remains asymptomatic and no harm occurs. How should the event be categorized using the NCC MERP Index?
Correct answer: D - Category D: the error reached the patient and required monitoring to confirm no harm
Before redesigning an automated-dispensing-cabinet refill process, a team scores wrong-pocket placement as Severity 9, Occurrence 4, and Detection 8. The risk priority number is S × O × D, and a higher Detection score means the failure is less likely to be found before harm. Which conclusion is accurate?
Correct answer: C - The RPN is 288, and poor detectability supports prioritizing this failure mode
A serialization review finds duplicated serial numbers and altered transaction data on a prescription-drug bottle. The dispenser quarantines the product and investigates; the manufacturer then confirms that it is counterfeit, establishing it as an illegitimate product. What must the dispenser do next under the DSCSA?
Correct answer: D - Notify FDA and appropriate immediate trading partners within 24 hours and retain required records for six years
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